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Given the known off-target effects of APR-246, we investigated whether the mutant-specific effects observed in OVCAR5 cells were attributable to intrinsic differences in redox homeostasis among the parental p53-null cell lines

To comprehensively include pathway-associated genes, we collected genes from the KEGG, REACTOME, and WIKI pathways

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When combined with lipotropic nutrients, this treatment may help support energy levels, reduce fatigue, and promote a more active lifestyle

FIGURE 5 The primary source of ROS in the endoplasmic reticulum is the formation of intramolecular disulfide bonds during the maturation of many secreted proteins and membrane proteins

Toxicology 417:6473