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Alternative Titration Approaches Some protocols use more aggressive titration, increasing every 1-2 weeks for faster dose finding

J Pineal Res 2003;34:75-8

The therapeutic efficacy of antidepressants is often accompanied by a range of side effects, which vary by drug class and individual patient response

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Additionally, there were nearly double the amount of side effects in the nortriptyline group [55]

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