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Papewalis C, Wuttke M, Jacobs B, Domberg J, Willenberg H, Baehring T, et al

The PPP, by contrast, branches from glucose-6-phosphate, generating NADPH and ribose-5-phosphate (for nucleotide synthesis) (73)

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For example, a large-scale study published in the Journal of the American Medical Association found that sertraline significantly improved symptoms of depression compared to a placebo

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They also found a significant reduction in fasting plasma glucose, serum insulin levels, homoeostasis model of assessment-insulin resistance and dehydroepiandrosterone sulphate (DHEAS) in the treated patients