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Fibrates are derivatives of fabric acid whose mechanism of action relies on the activation of the nuclear receptor peroxisome proliferator-activated receptors alpha (PPAR), which leads to several changes in metabolism, including a reduction in the production of APOC3 (the already mentioned physiological inhibitor LPL) and an increase in the expression of LPL, both alterations leading to a significant rise in LPL activity and a reduction in TG level in bloodstream [9,175-177]

Appetite control: methodological aspects of the evaluation of foods

Massey and Butler 1979

IR is further triggered by the increasing FFA concentrations via enhanced glucose dysregulation [23, 24]

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