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In central sensitization, the spinal cord and brain amplify incoming signals regardless of their original intensity

Gene Ther 7(1):75-9, 2000

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Two commonly prescribed medications for this condition are clonidine and propranolol

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58,62 These vesicles require high specificity for targeting and merging with recipient cells, which is why they consistently contain high concentrations of tetraspanin proteinssuch as CD9, CD63, CD81, and CD82that confer these essential characteristics