These two medications, known as GLP-1 agonists, have emerged as extremely effective weight loss and diabetes treatments, and have quickly gained star status as so-called miracle drugs for weight loss in celebrity and social media circles, leading to a surge in demand as well as a global shortage
The study indicates this may not be because the patients aren't producing enough glutathione, it may be because glutathione is being used at a higher rate in patients with type II diabetes
The most important serious side effects include acute pancreatitis (severe persistent abdominal pain radiating to the back, though clinical trials found similar pancreatitis rates to comparators), severe dehydration from persistent vomiting or diarrhea (signs include dizziness, decreased urination, extreme thirst), gallbladder disease including cholecystitis or cholelithiasis (right upper quadrant pain, fever, jaundice), severe allergic reactions (difficulty breathing, swelling of face or throat), and severe hypoglycemia when combined with insulin or sulfonylureas (confusion, loss of consciousness, seizures)
The microdosing tirzepatide chart provides additional context for those exploring non-standard dosing approaches
While their underlying mechanisms of action remain incompletely understood, it is clear that the common denominator between GLP-1R agonists and bariatric surgery is that they suppress food intake by targeting the brain
Potential Side Effects Your provider will walk you through the side effects patients report most often
