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Though tirzepatide has not yet been approved for treatment of obesity, these results suggest that it may be more efficacious than semaglutide 2.4 mg once weekly (an approved treatment for obesity) in people without diabetes, and it approaches the effectiveness of sleeve gastrectomy

However, the flip side is that if adverse effects occur, they may take weeks to months to fully resolve after discontinuation, as the drug slowly clears from the body

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The increase in testosterone can promote the development of secondary sexual characteristics and, in conjunction with follicle-stimulating hormone (FSH), support spermatogenesis