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10.1080/07315724.2002.10719248 J Am Coll Nutr
Our cryo-EM maps now provide a clear resolution of the D2 / core domain (residues 607767), corresponding to the structured region of the annotated D2a subdomain 60 , as well as the C-terminal portion of D2b (residues 860885), which contributes an additional helixstrand motif to the D2a / core (Fig
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This causes the rate of the GS reaction to come back down to normal despite the upregulation of CBS and GCS and cause the steady concentrations of cytosolic GSH and the blood concentrations of GSH and cysteine to decline below normal