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Cell culture studies demonstrate increased expression of synaptic proteins including PSD-95, synaptophysin, and synapsin following Dihexa treatment, confirming molecular mechanisms underlying the observed synaptogenic effects

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Wang R, Zhang JY, Zhang M, Zhai MG, Di SY, Han QH, et al

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When TTFD enters cells, GSH in red blood cells chemically reduces TTFD via a process called disulfide exchange (presumably using a protein called glutaredoxin)