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Sin embargo, medicamentos como semaglutida, dulaglutida, tirzepatida y liraglutida no requieren ajuste de dosis basado en la funcin renal, aunque se recomienda precaucin en enfermedad renal avanzada debido a la experiencia clnica limitada y el riesgo potencial de efectos gastrointestinales que podran causar deshidratacin

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This finding suggests that DNA demethylation regulates CYP2A6 expression via transcription factors such as PXR

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