This triple-agonist approach is believed to enhance the compounds efficacy in reducing energy intake, increasing energy expenditure, and modulating various metabolic processes
GLP-3 (Reta) Mechanism of Action Acts as an agonist at three receptors the GIP receptor, the GLP-1 receptor, and the glucagon receptor the defining "triple agonist" pharmacology that separates it from single- and dual-incretin compounds
peaks months 3-12
If weight is part of the treatment conversation, discuss the goal, risks, and alternatives with a licensed clinician
doi: 10.3389/fendo.2025.1605746 Received 03 April 2025 Accepted 20 June 2025 Published 07 July 2025 Corrected 15 August 2025 Volume 16 - 2025 Edited by Tatsuya Sato, Sapporo Medical University, Japan Reviewed by Nina Japundzic-Zigon, University of Belgrade, Serbia Jennifer E
Alongside GLP-1 weight loss, RxSpan MD's source material lists longevity products (such as NAD+, sermorelin, and glutathione) and hair products (built around ingredients like minoxidil, finasteride, and dutasteride), plus additional men's and women's telehealth categories
