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Despite a described effect of GLP-2 on osteoclast activity, the GLP-2 receptor has not been identified in human osteoclasts or any other bone-related cell type [69], except for immature human osteoblast cell lines MG-63 and TE-85 [69]

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doi: 10.1007/s12020-010-9362-0 92 ParkSLimWBazerFWSongG

The role of Hsp27 in chemotherapy resistance

In DXA body-composition analyses from the STEP 1 semaglutide program and the SURMOUNT-1 tirzepatide trial, lean mass decreased alongside fat mass, and the STEP 1 extension showed that many participants regained about two-thirds of their lost weight after stopping semaglutide, which is one more reason to protect muscle and training habits while the medication is working

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