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9.0 Patient counselling information Not to exceed the stated recommended daily dose

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Data for weight and HbA 1c were recorded at 0, 3, 6, and 12 months following initial medication changes after referral to our endocrine clinics (controls) or after start of either GLP-1 analog or SGLT-2 inhibitor

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This slight increase then leads to an increase in inflammatory cytokines (TNF-alpha, IL-1 beta) in macrophages[ref] Endoplasmic Reticulum (ER) stress, protein misfolding: The endoplasmic reticulum (ER) is an organelle in cells where newly synthesized proteins are folded, lipids are synthesized, and calcium is stored