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More consistent appetite suppression throughout the week (rather than a strong early-week effect followed by appetite returning toward the end)

In one study, about 3% of people taking the medication reported hair loss compared to 1% on placebo, suggesting a potential association for a small subset of users

H.et al (2023)

Interestingly, in pancreatic ductal adenocarcinoma (PDAC), uncoupling protein 2 (UCP2) can transport the aspartate derived from glutamine metabolism from mitochondria to the cytoplasm to generate NADPH, and silencing UCP2 can significantly inhibit the growth of PDAC

J Exp Med 215:2955

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