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Cardiac lesion estimation was based on the dilatation and congestion of blood vessels within the myocardium and coronary arteries using a scale ranging 03 (0: none

This is evident in the co-development of heart and digestive system tissues within human induced pluripotent stem cell (iPSC)-derived organoids, where the presence of endodermal tissue promotes the maturation of cardiac tissues [37]

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Such linear connectivity fails to account for the three-dimensional spatial organization critical to protein function 17