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Being on any combination therapy early in the disease is associated with enduring advantages, sometimes termed "legacy effects," in which benefits lag behind for a while [39], [41]

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Before considering Zepbound, our providers assess your medical history, current medications, and prior attempts at weight loss through lifestyle changes such as diet and physical activity

If nausea persists beyond 5 days post-injection or intensifies over consecutive weeks, this signals a need to pause dose escalation for an additional 24 weeks rather than pushing forward