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The three major routes of administration used for skin lightening are topical (creams, face washes), oral (capsules and sublingual/buccal tablets) and intravenous injections

Here is what women most commonly report: Injection site reactions

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doi: 10.1080/15548627.2020.1810918 12 SuYZhaoBZhouLZhangZShenYLvHet al

Therefore, additional studies focusing on long-term supplementation and its longitudinal effect on the TMAO metabolism and cardiovascular system are needed

Accessed 5 Feb 2022 Fajri M