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In vivo pharmacodynamic studies have shown that these liposomal formulations significantly improved antitumor efficacy, with increased tumor cell apoptosis [133]

Beyond achieving more effective glucose control and offering worthy weight loss, these medications achieved a reduction in rates of major adverse cardiovascular effects, heart failure, kidney disease, and cardiovascular death [13,14,15]

PMID: 33482069

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Shimizu, Clinical benefits of sodium-glucose cotransporter 2 inhibitors and the mechanisms underlying their cardiovascular effects

They are not general chemical surveys