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CJC-1295 is a synthetic GHRH analog built on the first 29 amino acids of GHRH with a Drug Affinity Complex (DAC) lysine modification that enables covalent binding to serum albumin

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Nat Rev Nephrol 15:577589 Schaefer F, Baumann G, Haffner D, Faunt LM, Johnson ML, Mercado M, Ritz E, Mehls O, Veldhuis JD (1996) Multifactorial control of the elimination kinetics of unbound (free) growth hormone (GH) in the human: regulation by age, adiposity, renal function, and steady state concentrations of GH in plasma

DOI: 10.1016/j.cmet.2012.04.003 42

Funding Statement The authors are supported by grants from the National Institute of Health (NIH/NCCIH)-(5R33AT010637-01A1 and 3R33 AT010637-02S1) and the Malcolm Feist Endowed Chair in Diabetes

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