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The preference of DHDPR for NADH or NADPH varies across species, with orthologues in E

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There are only few case reports where vitamin B12 deficiency was solely attributed as the cause of pyrexia.[2,3,4] The exact cause of pyrexia in megaloblastic anemia is not known but a proposed mechanism is that megaloblastic anemia leads to hyperplasia and thus increased activity within the bone marrow leading to systemic pyrexia

doi:10.1073/pnas.0606544103

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