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H8 suppresses 11-HSD1 to ameliorate adipose tissue lipid metabolic disorders in mice As shown in Fig

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Researchers associate a vitamin B12 deficiency with various health issues, megaloblastic anemia neurological changes and disorders infertility depression neural tube defects and developmental delays in children born to those with a vitamin B12 deficiency Supplementation may help to reduce the risk of these health issues

The metabolic improvements associated with GLP-1 agonist therapyincluding weight loss, improved glycaemic control, and potential benefits in MASLD (formerly known as non-alcoholic fatty liver disease)could address multiple health concerns simultaneously, though effects specifically in alcohol-related liver disease are not established

Cancer Discov 8(12):1654, 2018