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The significance of differences in protein abundance was determined with a Paired T-test for sibling cohort comparisons and a T-test for comparisons of unrelated groups such as Stage 1 versus Stage 3

The functional pathways of Ru-PC nano-enzymes varied significantly across different environments

As an important transcription factor, Nrf2 can not only regulate SLC7A11 transcription, but also up-regulate the expression of GSS and GCLC, which are key rate-limiting enzymes for GSH synthesis (Dodson et al., 2019)

91, 1005910063.10.1073/pnas.91.21.10059 35 MayM

Thyroid myopathy typically affects proximal muscle groups but can also lead to weakness of distal and bulbar muscles