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Naltrexone/bupropion (Mysimba) is licensed for adults with BMI 30 kg/m (or 27 kg/m with weight-related comorbidities)

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The adverse effect profile of baclofen encompasses transient sedation, confusion, muscle weakness, and potential neuropsychiatric disturbances, while the life-threatening consequences of abrupt withdrawalparticularly with intrathecal administrationdemand vigilant monitoring and patient education