Indeed, the stronger relationship between elevated circulating homocysteine levels and atherothrombotic disease observed in retrospective case-controlled studies than in prospective studies might be explained by the younger average age of subjects sustaining a coronary event in retrospective studies (in the positive study by Wald et al (1998), see the age comparison between retrospective and prospective studies)
Yes, we advise against it
Reduced TNSALP activity affects the hydrolysis of phosphate esters including substrates like PLP and contributes to the decreased ALP levels observed in HPP
Use a higher concentration or split into two injections.* At concentrations of 10 mg/mL and above, even the maximum 15 mg dose fits within a 1 mL syringe (75 units at 20 mg/mL)
Preparation Before Reconstitution Proper preparation ensures sterility and prevents contamination of both the peptide vial and the bacteriostatic water
Sikiric, P., Seiwerth, S., Rucman, R., Turkovic, B., Stancic Rokotov, D., Brcic, L., & Sebecic, B