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As a common complication of diabetes, diabetic wounds have garnered increasing research attention in recent years, primarily focusing on cell types involved in wound repair, such as macrophages, fibroblasts, endothelial cells, and keratinocytes
No significant organ toxicity has been observed in standard histological analyses of animals treated with therapeutic-range doses
Published clinical trials used continuous daily administration for 12-24 weeks without scheduled breaks, establishing this as a viable approach with maintained safety throughout the treatment period
21792191, Oct
When a compound has such a narrow target, the potential for off-target side effects is inherently limited