It is a synthetic, engineered peptide derived from the transcription factor FOXO4
Abnormalities in the expression or function of FOXO6 have been identified as a pathophysiological basis for the development of fasting hyperglycemia and hyperlipidemia, which are serious metabolic complications in diabetic patients
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Because it raises GH and IGF-1, the relevant monitoring is for the effects of higher GH: blood sugar can rise, and IGF-1 should be kept within a sensible range rather than pushed indefinitely
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