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In another glioma study targeting APLNR with a competitive antagonist reduced tumor growth in mice [190]

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33 by dissolving the solute in ethanol followed by dilution with phosphate buffered saline (PBS) to concentrations of 0, 50, 100, 150 and 200 M

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Furthermore, the hedonic response to sucrose in humans was shown to associate with parental history of AUD, suggesting that hedonic response to sucrose may indicate a genetic risk for AUD (Kampov-Polevoy et al., 2001, 2003)