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Ischemia and hypoxia can disrupt the microbial composition of the gut microbiome, which can lead to intestinal barrier dysfunction and bacterial translocation [12]

It is designed to bind GHRH receptors on pituitary somatotroph cells, prompting the body's own pituitary gland to release growth hormone (GH), which in turn raises downstream IGF-1 levels

Ohnishi, M

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Cagrilintide works through an entirely different receptor system