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Each parameter was graded 04 (0 = normal, 1 = minimal, 2 = mild, 3 = moderate, 4 = severe)

Patients with certain variants may show higher baseline inflammatory markers or slower adaptation to rapid metabolic change

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doi: 10.1016/j.it.2008.02.012 217 IshikawaTTakizawaTIwakiJMishimaTUi-TeiKTakeshitaTet al

Protocolos de investigacin Los protocolos en literatura preclnica varan ampliamente segn modelo