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Mechanism of Action While previous studies have reported that GIP alone has no significant role as a therapeutic agent upon insulin levels in T2D patients, with all effects appearing to be accounted for by GLP-1, more recent research has contradicted this claim [95]

This can alter the normal balance in synaptic plasticity and lead to cognitive decline (90)

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Taking Rybelsus exactly as prescribed and eating smaller, more frequent meals may help reduce these effects

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[11] [12] Common adverse effects include gastrointestinal symptoms such as nausea, vomiting, diarrhea, and decreased appetite, which are generally mild to moderate in severity and tend to diminish over time