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Mild bruising or soreness at the needle site can happen but fades in a day or two

The LEADER trial for liraglutide and SUSTAIN-6 for semaglutide established cardiovascular benefit for that class

A 2024 systematic review found that GLP-1 receptor agonists may help reduce abdominal pain and improve bowel habits in people with IBS 4

That is why regular TSH checks matter early on, and why you should not change your levothyroxine routine or timing without your prescribing provider directing it