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In particular, low micromolar to millimolar concentrations of Trolox are used in cell culture and in vivo applications ( Figure 5A , AX preincubation with PBS or Trolox did not significantly reduce AX-HSA adduct formation with respect to the adducts formed by the freshly prepared mixtures, whereas preincubation with TCEP showed a tendency towards decreasing adduct levels

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While the vast majority of nevi in the pediatric population are benign, the rising incidence of melanoma among the general population has increased the awareness of pigmented lesions and concern for malignant potential

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