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For instance, under stressful circumstances, ATF4 and NRF2 interact at the SLC7A11 promoter and work together to synergistically control SLC7A11 transcription ( 2.1.2 GPX4/GSH Ursini et al

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Methods: A 12-day substance repeated exposure scheme was established to explore potential lung effects through analysis of bioactivity readouts from the tissue integrity and functionality, cytokine/chemokine secretion, and transcriptomics

If L-carnitine supplementation proves ineffective, alternative interventions, such as dietary adjustments or targeted pharmacological agents affecting related pathways, should be explored