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however, resistance to oxaliplatin remains a significant clinical challenge in HCC treatment

The literature data indicate that the amino group in the structure of amlodipine may act as a free radical acceptor and bind reactive forms of sugars, thereby inhibiting AGEs formation 86

The majority of QIs was reduced back to the respective parent compound (50% of AQ-QI and 80% of DEAQ-QI), presumably by the action of endogenous antioxidants and/or reductases, e.g., quinone reductases ( Figure 5B )

[DOI] [PubMed] [Google Scholar] 36.Palmer CS, Traub RJ, Robertson ID