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This makes it particularly suitable for a more immediate effect, just before or immediately after sports activity

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When should I take L-citrulline or L-arginine for best results?+ For exercise performance, take citrulline malate 60 minutes before your workout

It reduces methylationdriven consumption of NAM, increases substrate availability for NAD+ synthesis, and promotes NAD+ biosynthesis to elevate intracellular NAD+ levels

Therefore, a larger RCT is highly warranted, especially in the field of dose and duration