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The two are listed as side effects of the medication

MT1's two structural modifications address this limitation directly: Nle4 substitution replaces the oxidation-prone methionine at position 4 with norleucine, a structurally similar but metabolically stable residue

doi: 10.1542/peds.111.3.477 46

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This interaction also hints at DSIP's potential role in managing stress tolerance, given the significant influence of alpha 1-adrenergic signaling in stress-related processes

These natural compounds are often rich in antioxidants, which are capable of neutralizing free radicals and reducing oxidative stress [201]