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Doxorubicin- and daunorubicin-glutathione conjugates, but not unconjugated drugs, competitively inhibit leukotriene C4 transport mediated by MRP/GS-X pump
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However, and interestingly, data also suggested that while GSTP1-1 engages TRAF2 in its dimeric form, only one monomer is involved in binding and therefore the other may still be catalitically competent 30
Gastrointestinal dysfunction in neurological and neurodegenerative disorders
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