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Firstly, the dosage varies significantly

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Quinlan et al., 2013), complex I and complex III (Venditti et al., 2013) have been shown to be the most important sources of mitochondrial superoxide generation, although significant production of ROS in complex II has recently also been reported (Quinlan et al., 2012)

Additionally, recent studies have found that the expression of GPX4 and GSH was disordered in rats administered DOX [92]