Joint pathology including osteoarthritis, post-traumatic arthritis, and inflammatory arthropathies represent additional potential applications
Thomas 2015)
There were four test groups: metformin alone, metformin plus a sulfonylurea and then randomised into a group with either Rybelsus 7mg, Rybelsus 14mg, or Januvia 100mg
Polymeric nanoparticles are chosen for TDDS because they easily toss chemical and physical properties, minimising drug reduction and boosting SC penetration
Risks : Possible amplified side effects, such as injection site reactions, headaches, or water retention

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