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In addition, the presence of immunosuppressive cytokines, such as transforming growth factor- (TGF-) and IL-10, contribute to the resistance of prostate cancer to immune checkpoint inhibitors by constructing an immunosuppressive tumor microenvironment and inhibiting the function of effector T cells (49)

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Overall, Glp1r + Chat + neurons comprised a very small portion of any cholinergic population

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HGH therapy introduces synthetic human growth hormone directly into the body, bypassing the pituitary entirely