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528 CQ also modulates the expression and activity of the transcription factor Nurr1, which influences Treg differentiation, providing an additional mechanistic link between autophagy-related pathways and immune tolerance

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Despite promising results, challenges persist in optimizing bioavailability and metabolic stability

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The hormone GLP-1 is also a neurotransmitter and communicates directly with an area in the brain that regulates appetite, called the hypothalamus