Common: nausea (especially during dose increasesusually mild and transient), constipation or diarrhea, occasional vomiting, fatigue in first weeks, decreased appetite (the desired effect, but worth noting)
Once the supplies arrive, patients must attend a training session to learn how to self-administer the weekly semaglutide injections
Proven to be safe with no negative side effects with long-term use
Polkowska-Pruszyska B, Gerkowicz A, Krasowska D
At the molecular level, excessive androgen receptor activation has been shown to stimulate phosphoinositide-3-kinase (PI3K)/Akt and mitogen-activated protein kinase (MAPK) signalling pathways, promoting cardiomyocyte hypertrophy while simultaneously enhancing mitochondrial oxidative injury (73)
This is separate from the GH-releasing activity