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Quick Answer: Hot flashes are not a recognized adverse effect of tirzepatide in FDA labeling, though some patients report vasomotor symptoms that may relate to weight loss, hormonal changes, or other factors requiring clinical evaluation

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This means once you draw from the vial and recap it properly, the remaining solution stays protected not just for a few hours, but for up to 28 days under normal storage conditions

However, very high doses (usually over 2,000mg) can cause loose stools in some people