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Patients may experience: Persistent fatigue and weakness Breathlessness on exertion Pallor or a slightly yellowish tinge to the skin Heart palpitations Neurological symptoms are of particular clinical concern, as nerve damage caused by prolonged B12 deficiency can be irreversible if not treated promptly
These changes correlate with weight loss magnitude, particularly reduction in visceral adiposity and neck circumference
KWONG: These are clearly life-changing medications, and also, it seems a big commitment
The UK Reference Nutrient Intake is 0.75g per kg body weight daily, but during weight loss, higher intakes of 1.0-1.5g/kg/day may be beneficial to preserve muscle mass
Front Endocrinol (Lausanne) 11:280
Mizuno, S., Nakamura, T., Improvement of Sepsis by Hepatocyte Growth Factor, an Anti-Inflammatory Regulator: Emerging Insights and Therapeutic Potential
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