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As the NAC samples of interest were from a DMEM solution, it was important that the matrices present (amino acids, water soluble vitamins, sodium pyruvate, HEPES, glucose, minerals, sodium carbonate, sodium bicarbonate, salts, etc.) in those samples did not interfere with the NAC quantitation

The expression of SOD is reported to be reduced due to COVID-19 infection in the lungs of elderly patients (43)

Glutathione is a very important antioxidant in our bodies and is formed by three amino acids: glutamate (or glutamic acid), glycine and cysteine, the basic amino acid from which NAC is formed

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The driving force for transport is provided by both the substrate and H + -concentration gradients, with the pH gradient determining the extent of transport activity (Juel 1997, Halestrap and Price 1999)