Lipoic acid inhibits expression of ICAM-1 and VCAM-1 by CNS endothelial cells and T cell migration into the spinal cord in experimental autoimmune encephalomyelitis
This size-based penetration advantage is central to its topical research applications and helps explain why laboratory studies have consistently demonstrated biological activity following topical application models
It is key in supporting immune function, metabolism, forming sperm cells, tissue building and repair, and helping with certain enzyme functions
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Similar content being viewed by others Log in or create a free account to read this content Gain free access to this article, as well as selected content from this journal and more on nature.com or Abbreviations AA: amino acid AOPP: advanced oxidized protein products ASR: absolute synthesis rate FSR: fractional synthesis rate GSH: glutathione ROS: reactive oxygen species References Richmond S, Goldsmith JP 2006 Air or 100% oxygen in neonatal resuscitation
Ezz El-Arab AM, Girgis SM, Hegazy EM, Abd El-Khalek AB