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The sequence alignments were performed with the MSA program Clustal Omega (v0(1.2.4)) and further analyzed using the software ESPript3.0 (v3.0.10) 130,131

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Most of peptidebased vaccines are based on epitope peptides stimulating CD8+ T cells or CD4+ T helper cells to target tumourassociated antigens (TAAs) or tumourspecific antigens (TSAs)

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