c-MET pathway acts on several downstream effectors including phospholipase C gamma (PLC), cellular Src kinase (c-Src), phosphotidylinsitol-3-OH kinase (PI3K), alpha serine/threonine-protein kinase (Akt), mitogen-activated protein kinase (MAPK), and wingless-related integration site (Wnt) pathways
The primary endpoints for this study were change in body weight and body composition (assessed by dual x-ray absorptiometry [DXA] scanning for total mass, fat mass, and lean mass), and we also assessed food intake, glycated hemoglobin (HbA1c%), and lipid profiles
Q., Zhu, S
Home-cage locomotor activity was measured also along the treatments by means of an extensiometric weight transducer integrated below each cage
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