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Transfusion 55 , 491498

doi:10.1152/japplphysiol.00945.2010

Edmonson, et al

Yes, taking both is generally safe as B vitamins are water-soluble, but you may receive excessive amounts of certain vitamins, particularly B6 and niacin

[47] A 2024 systematic review of 6 studies found that while lean body mass was unchanged in some cases, there were instances of significant decreases in lean body mass (040%)