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The drug has endured numerous clinical trials, one of the largest of which saw a 15.8% reduction in body weight after 68 weeks.7 For a 250lb person, that would equate to a loss of 39.5 pounds in a little over a year

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Research protocols show significant improvement in survival compared to chemotherapy alone in preclinical melanoma models, providing researchers with frameworks for studying "one-two punch" strategies that combine senolytic and targeted cancer therapies

doi: 10.1136/jnnp-2018-320050 148 McGinleyM

TB-500 and cancer research: Huang et al